Other Publications

Title and authors

1

Yang, C.-Y., Lin, Y.-T., Lin, L.-J., Chang, Y.-H., Chen, H.-Y., Wang, Y.-P., Shih, J.-Y., Yu, C.-J., Yang, P.-C., 2023, “Stage Shift Improves Lung Cancer Survival: Real-World Evidence.”, Journal of Thoracic Oncology, 18(1), 47-56.

2

Yu CH, Wu G, Chang CC, Jou ST, Lu MY, Lin KH, Chen SH, Wu KH, Huang FL, Cheng CN, Chang HH, Hedges D, Wang JL, Yen HJ, Li MJ, Chou SW, Hung CT, Lin ZS, Lin CY, Chen HY, Ni YL, Hsu YC, Lin DT, Lin SW, Yang JJ, Pui CH, Yu SL, Yang YL., 2022, “Sequential Approach to Improve the Molecular Classification of Childhood Acute Lymphoblastic Leukemia.”, J Mol Diagn., 24(11):1195-1206.

3

Mei-Hsuan Lee, Ping-Feng Wu, Tzu-I Chen, Chi Chan, Hsi-Hsun Lin, Yi-Hsiang Huang, Hsuan-Yu Chen, Yi-Tsung Lin, Chien-Jen Chen, 2022, “Tenofovir use is associated with a decreased risk of hepatocellular carcinoma among men with HIV irrespective of coinfection status.”, JHEP Reports, 100634.

4

Lai IC, Liao CH, Hu MH, Chang CL, Lai GM, Chiou TJ, Hsia S, Tsai WL, Lin YY, Chuang SE, Whang-Peng J, Chen HY, Yao CJ., 2022, “Selenium Yeast and Fish Oil Combination Diminishes Cancer Stem Cell Traits and Reverses Cisplatin Resistance in A549 Sphere Cells.”, Nutrients, 14(15):3232.

5

Chang WH, Chen YJ, Hsiao YJ, Chiang CC, Wang CY, Chang YL, Hong QS, Lin CY, Lin SU, Chang GC, Chen HY, Chen YJ, Chen CH, Yang PC, Yu SL., 2022, “Reduced symmetric dimethylation stabilizes vimentin and promotes metastasis in MTAP-deficient lung cancer.”, EMBO Rep., 23(8):e54265.

6

Hsu YC, Huang SM, Chang LC, Chen YM, Chang YH, Lin JW, Lin CC, Chen CW, Chen HY, Chiu HM, Yu SL., 2022, “Screening of early-staged colorectal neoplasia by clonal hematopoiesis-based liquid biopsy and machine-learning.”, Am J Cancer Res., 12(3):1088-1101.

7

Lin FC, Chen CY, Lin CW, Wu MT, Chen HY, Huang P., 2022, “Air Pollution Is Associated with Cognitive Deterioration of Alzheimer's Disease”, Gerontology, 68, 53-61.

8

Hsin-Yi Huang, Chih-Hsiang Yu, Yung-Li Yang, Ya-Hsuan Chang, Shiann-Tarng Jou, Kai-Hsin Lin, Meng-Yao Lu, Hsiu-Hao Chang, Shu-Wei Chou, Yu-Ling Ni, Dong-Tsamn Lin, Hsuan-Yu Chen, Steven Shinn-Forng Peng, Meng-Fai Kuo, Shih-Hung Yang, 2022, “Integration of immunohistochemistry, RNA sequencing, and multiplex ligation-dependent probe amplification for molecular classification of pediatric medulloblastoma”, Pediatr Blood Cancer, 00e29569.

9

Chang CH, Shih AC, Chang YH, Chen HY, Chao YT, Hsu YC., 2021, “The Prognostic Significance of PD1 and PDL1 Gene Expression in Lung Cancer: A Meta-Analysis”, Front Oncol., 11, 759497.

10

Hsiao, Y. J., Chang, W. H., Chen, H. Y., Hsu, Y. C., Chiu, S. C., Chiang, C. C., Chang, G. C., Chen, Y. J., Wang, C. Y., Chen, Y. M., Lin, C. Y., Chen, Y. J., Yang, P. C., Chen, J.,  Yu, S. L., 2021, “MITF functions as a tumor suppressor in non-small cell lung cancer beyond the canonically oncogenic role”, Aging, 13, 646–674.

11

Wang, C. C., Lin, S. Y., Huang, Y. H., Hsieh, C. H., Chang, H. H., Chen, H. Y., Weng, C. W., Chang, G. C., Yu, S. L., Chen, J. J., 2021, “Paired-like homeodomain 2B contributes to tumour progression and anti-autophagy in human lung cancer”, American Journal of Cancer Research, 11, 4900–4918.

12

Yang YL, Jaing TH, Chen SH, Liu HC, Hung IJ, Lin DT, Yang CP, Peng CT, Lin KH, Hsiao CC, Jou ST, Chen JS, Lin MT, Wang SC, Chang TK, Huang FL, Cheng CN, Wu KH, Sheen JM, Chen SH, Lu MY, Hung GY, Yen HJ, Hsieh YL, Wang JL, Chang YH, Chang HH, Yeh TC, Weng TF, Hou JY, Chen BW, Chen RL, Wang LY, Ho WL, Chen YC, Cheng SN, Chao YH, Yang SH, Huang TH, Chou SW, Lin CY, Chen HY, Chao YY, Liang DC, Chang TT, 2021, “Treatment outcomes of pediatric acute myeloid leukemia: a retrospective analysis from 1996 to 2019 in Taiwan”, Sci Rep., 11, 5893

13

Hsu HH, Liu YH, Chen HY, Chen PH, Chen KC, Hsieh MJ, Lin MW, Kuo SW, Huang PM, Chao YK, Wu CF, Wu CY, Chiu CH, Chen WH, Wen CT, Liu CY, Wu YC, Chen JS., 2021, “Vicryl Mesh Coverage Reduced Recurrence After Bullectomy for Primary Spontaneous Pneumothorax”, Ann Thorac Surg., 112, 1609-1615.

14

Lee, P. J., Ho, C. C., Ho, H., Chen, W. J., Lin, C. H., Lai, Y. H., Juan, Y. C., Chu, W. C., Lee, J. H., Su, S. F., Chen, H. Y., Chen, J., Chang, G. C., Li, K. C., Yang, P. C., & Chen, H. W., 2021, “Tumor microenvironment-based screening repurposes drugs targeting cancer stem cells and cancer-associated fibroblasts”, Theranostics, 11, 9667–9686.

15

Hsin-Jung Li, Feng-Yi Ke, Chia-Ching Lin, Mei-Yi Lu, Yi-Huei Kuo, Yi-Ping Wang, Kang-Hao Liang, Shin-Chang Lin, Ya-Hsuan Chang, Hsuan-Yu Chen, Pan-Chyr Yang and Han-Chung Wu, 2021, “ENO1 Promotes Lung Cancer Metastasis via HGFR and WNT Signaling–Driven Epithelial-to-Mesenchymal Transition”, Cancer Res., 81, 4094-4109

16

Wang D-S, Yu C-H, Lin C-Y, Chang Y-H, Lin K-H, Lin D-T, Jou S-T, Lu M-Y, Chang H-H, Lin S-W, Chen H-Y, Yang Y-Ll, 2021, “Childhood acute lymphoblastic leukemia mercaptopurine intolerance is associated with NUDT15 variants”, Pediatric Research, 89, pages217–222

17

Tu DG, Chen HY, Yao WJ, Hung YS, Chang YK, Chang CH, Wang YW., 2021, “Verification of the Efficacy of New Diagnostic Criteria for Retropharyngeal Nodes in a Cohort of Nasopharyngeal Carcinoma Patients”, Int J Med Sci., 18, 3463-3469.

18

Lu CS, Lin CW, Chang YH, Chen HY, Chung WC, Lai WY, Ho CC, Wang TH, Chen CY, Yeh CL, Wu S, Wang SP, Yang PC., 2020, “Antimetabolite pemetrexed primes a favorable tumor microenvironment for immune checkpoint blockade therapy.”, J Immunother Cancer,8(2): e001392.

19

Yu CH, Chang YH, Wang DS, Jou ST, Lin CY, Lin KH, Lu MY, Raghav L, Chang HH, Wu KH, Chou SW, Ni YL, Lin DT, Lin SW, Chen HY, Yang YL., 2020, “Determination of NUDT15 variants by targeted sequencing can identify compound heterozygosity in pediatric acute lymphoblastic leukemia patients.”, Sci Rep., 10(1):14400.

20

Huang YH, Liao SF, Khor SS, Lin YJ, Chen HY, Chang YH, Huang YH, Lu SN, Lee HW, Ko WY, Huang C, Liu PC, Chen YJ, Wu PF, Chu HW, Wu PE, Tokunaga K, Shen CY, Lee MH., 2020, “Large-scale genome-wide association study identifies HLA class II variants associated with chronic HBV infection: a study from Taiwan Biobank.”, Aliment Pharmacol Ther., 52(4):682-691.

21

Yu CH, Lin TK, Jou ST, Lin CY, Lin KH, Lu MY, Chen SH, Cheng CN, Wu KH, Wang SC, Chang HH, Li MJ, Ni YL, Su YN, Lin DT, Chen HY, Harrison CJ, Hung CC, Lin SW, Yang YL., 2020, “MLPA and DNA index improve the molecular diagnosis of childhood B-cell acute lymphoblastic leukemia.”, Sci Rep, 10, 11501.

22

Huang C, Chen SP, Huang YH, Chen HY, Wang YF, Lee MH, Wang SJ., 2020, “HLA class I alleles are associated with clinic-based migraine and increased risks of chronic migraine and medication overuse.”, Cephalalgia, 40(5):493-502.

23

Wang YW, Ho SY, Lee SW, Chen CC, Litsu S, Huang WT, Yang CC, Lin CH, Chen HY, Lin LC., 2020, “Induction Chemotherapy Improved Long Term Outcomes in Stage IV Locoregional Advanced Nasopharyngeal Carcinoma.”, Int J Med Sci., 17(5):568-576.

24

Wu JE, Wu YY, Tung CH, Tsai YT, Chen HY, Chen YL, Hong TM., 2020, “DNA methylation maintains the CLDN1-EPHB6-SLUG axis to enhance chemotherapeutic efficacy and inhibit lung cancer progression.”, Theranostics, 10(19):8903-8923.

25

Huang Y-H, Khor S-S, Zheng X, Chen H-Y, Chang Y-H, Chu H-W, Wu P-E, Lin Y-J, Liao S-F, Shen C-Y, Tokunaga K, Lee M-H, 2020, “A high-resolution HLA imputation system for the Taiwanese population: a study of the Taiwan Biobank”, The Pharmacogenomics Journal, 20:695-704.

26

Lee JH, Chen HY, Hsu FM, Chen JS, Liao WY, Shih JY, Yu CJ, Chen KY, Tsai TH, Yang JC., 2019, “Cranial Irradiation for Patients with Epidermal Growth Factor Receptor (EGFR) Mutant Lung Cancer Who Have Brain Metastases in the Era of a New Generation of EGFR Inhibitors.”, Oncologist, 24(12):e1417-e1425.

27

Chao CT, Yuan TH, Yeh HY, Chen HY, Huang JW, Chen HW., 2019, “Risk Factors Associated With Altered Circulating Micro RNA -125b and Their Influences on Uremic Vascular Calcification Among Patients With End-Stage Renal Disease.”, J Am Heart Assoc., 8(2):e010805.

28

Lin CA, Yu SL, Chen HY, Chen HW, Lin SU, Chang CC, Yu CJ, Yang PC, Ho CC, 2019, “EGFR-Mutant SCLC Exhibits Heterogeneous Phenotypes and Resistance to Common Antineoplastic Drugs.”, Journal of Thoracic Oncology, 14(3), 513-526.

29

Emura T, Matsui S, Chen HY, 2019, “compound.Cox: Univariate feature selection and compound covariate for predicting survival.”, Computer methods and programs in biomedicine, 168, 21-37.

30

Mei-Hsuan Lee, Yu-Han Huang, Hsuan-Yu Chen, Charles Seik-Soon Khor, Ya-Hsuan Chang, Yu-Ju Lin, Chin-Lan Jen, Sheng-Nan Lu, Hwai-I Yang, Nao Nishida, Masaya Sugiyama, Masashi Mizokami, Yong Yuan, Gibert L'Italien, Katsushi Tokunaga, Chien-Jen Chen, for the REVEAL-HCV cohort, 2018, “Human Leukocyte Antigen Variants and Risk of Hepatocellular Carcinoma Modified by HCV Genotypes: A Genome-wide Association Study” Hepatology, 67, 651-661.

31

Chia-Ying Hsu, Gee-Chen Chang, Yi-Ju Chen, Yi-Chiung Hsu, Yi-jing Hsiao, Kang-Yi Su, Hsuan-Yu Chen, Chien-Yu Lin, Jin-Shing Chen, Yu-Ju Chen, Qi-Sheng Hong, Wen-Hui Ku, Chih-Ying Wu, Bing-Ching Ho, Ching-Cheng Chiang, Pan-Chyr Yang and Sung-Liang Yu, 2018, “FAM198B is Associated with Prolonged Survival and Inhibits Metastasis in Lung Adenocarcinoma via Blockage of ERK-Mediated MMP-1 Expression” Clin. Ca. Res., 24(4): 916-926

32

Chen PH, Bendris N, Hsiao YJ, Reis CR, Mettlen M, Chen HY, Yu SL, Schmid SL., 2017, “Crosstalk between CLCb/Dyn1-Mediated Adaptive Clathrin-Mediated Endocytosis and Epidermal Growth Factor Receptor Signaling Increases Metastasis.”, Dev Cell, (3):278-288.e5.

33

Siu MK, Chen WY, Tsai HY, Chen HY, Yin JJ, Chen CL, Tsai YC, Liu YN., 2017, “TCF7 is suppressed by the androgen receptor via microRNA-1-mediated downregulation and is involved in the development of resistance to androgen deprivation in prostate cancer.”, Prostate Cancer Prostatic Dis., 20(2):172-178.

34

Hao-Wei Cheng, Yi-Fang Chen, Jau-Min Wong, Chia-Wei Weng, Hsuan-Yu Chen, Sung-Liang Yu, Huei-Wen Chen, Ang Yuan, Jeremy J.W. Chen, 2017, “Cancer cells increase endothelial cell tube formation and survival by activating the PI3K/Akt signalling pathway” Journal of Experimental & Clinical Cancer Research, 36:27

35

Lin P-Y, Chen H-Y, Yu S-L, Yang P-C. 2017, “Turning Diversity Toward Precision” JNCI: Journal of the National Cancer Institute, 109(1):1-2.

36

Chao, Chia-Ter, Liu, You-Pi, Su, Sheng-Fang, Yeh, Hsiang-Yuan, Chen, Hsuan-Yu, Lee, Pei-Jung, Chen, Wan-Jiun, Lee, Yee-Ming, Huang, Jenq-Wen, Chiang, Chih-Kang, Hung, Kuan-Yu, Chen, Huei-Wen, 2017, “Circulating MicroRNA-125b Predicts the Presence and Progression of Uremic Vascular Calcification” Arteriosclerosis, Thrombosis, and Vascular Biology, 37, 1402-1414.

37

Tseng, Chien-Hua, Chiang, Chun-Ju, Tseng, Jeng-Sen, Yang, Tsung-Ying, Hsu, Kuo-Hsuan, Chen, Kun-Chieh, Wang, Chih-Liang, Chen, Chih-Yi, Yen, Sang-Hue, Tsai, Chun-Ming, Huang, Ming-Shyan, Ho, Chao-Chi Yu, Chong-Jen, Tsai, Ying-Huang, Chen, Jin-Shing, Chou, Teh-Ying, Tsai, Ming-Hsun, Chen, Hsuan-Yu, Su, Kang-Yi, Chen, Jeremy J. W. Chen, Huei-Wen, Yu, Sung-Liang, Liu, Tsang-Wu, Chang, Gee-Chen, 2017, “EGFR mutation, smoking, and gender in advanced lung adenocarcinoma” Oncotarget, 8:  98384-98393

38

Hsu KH, Tseng JS, Wang CL, Yang TY, Tseng CH, Chen HY, Chen KC, Tsai CR, Yang CT, Yu SL, Su KY, Yu CJ, Ho CC, Hsia TC, Wu MF, Chiu KL, Liu CM, Yang PC, Chen JJ, Chang GC., 2016, “Higher frequency but random distribution of EGFR mutation subtypes in familial lung cancer patients.”, Oncotarget, 7(33):53299-53308.

39

Chien-Hua Tseng, Kun-Chieh Chen, Kuo-Hsuan Hsu, Jeng-Sen Tseng, Chao-Chi Ho, Te-Chun Hsia, Kang-Yi Su, Ming-Fang Wu, Kuo-Liang Chiu, Chien-Ming Liu, Tzu-Chin Wu, Hung-Jen Chen, Hsuan-Yu Chen, Chi-Sheng Chang, Chung-Ping Hsu, Jiun-Yi Hsia, Cheng-Yen Chuang, Chin-Hung Lin, Jeremy J.W. Chen, Kuan-Yu Chen, Wei-Yu Liao, Jin-Yuan Shih, Sung-Liang Yu, Chong-Jen Yu, Pan-Chyr Yang, Tsung-Ying Yang, Gee-Chen Chang, 2016, “EGFR mutation and lobar location of lung adenocarcinoma.”, Carcinogenesis, 37(2): 157–162.

40

Lin CW, Wang LK, Wang SP, Chang YL, Wu YY, Chen HY, Hsiao TH, Lai WY, Lu HH, Chang YH, Yang SC, Lin MW, Chen CY, Hong TM, Yang PC., 2016, “Daxx inhibits hypoxia-induced lung cancer cell metastasis by suppressing the HIF-1α/HDAC1/Slug axis.”, Nat Commun, 7:13867.

41

Chen CH, Chang WH, Su KY, Ku WH, Chang GC, Hong QS, Hsiao YJ, Chen HC, Chen HY, Wu R, Yang PC, Chen JJ, Yu SL., 2016, “HLJ1 is an endogenous Src inhibitor suppressing cancer progression through dual mechanisms.”, Oncogene, 35(43):5674-5685.

42

Tseng JS, Su KY, Yang TY, Chen KC, Hsu KH, Chen HY, Tsai CR, Yu SL, Chang GC., 2016, “The emergence of T790M mutation in EGFR-mutant lung adenocarcinoma patients having a history of acquired resistance to EGFR-TKI: focus on rebiopsy timing and long-term existence of T790M.”, Oncotarget, 7(30):48059-48069.

43

Hsiao YJ, Su KY, Hsu YC, Chang GC, Chen JS, Chen HY, Hong QS, Hsu SC, Kang PH, Hsu CY, Ho BC, Yang TH, Wang CY, Jou YS, Yang PC, Yu SL., 2016, “SPANXA suppresses EMT by inhibiting c-JUN/SNAI2 signaling in lung adenocarcinoma.”, Oncotarget, 7(28):44417-44429

44

Su TJ, Ku WH, Chen HY, Hsu YC, Hong QS, Chang GC, Yu SL, Chen JJ., 2016, “Oncogenic miR-137 contributes to cisplatin resistance via repressing CASP3 in lung adenocarcinoma.”, Am J Cancer Res, 6(6):1317-30

45

Hsieh PY, Chen KY, Chen HY, Sheng WH, Chang CH, Wang CL, Chiag PY, Chen HP, Shiao CW, Lee PC, Tai HC, Chien HF, Yu PJ, Lin BR, Lai YH, Chen JS, Lai HS, 2016, “Postoperative Showering for Clean and Clean-contaminated Wounds: A Prospective, Randomized Controlled Trial” Ann Surg., 263(5),931- 936

46

Chang WH, Ho BC, Hsiao YJ, Chen JS, Yeh CH, Chen HY, Chang GC, Su KY, Yu SL, 2016, “JAG1 Is Associated with Poor Survival through Inducing Metastasis in Lung Cancer.”, PloS one, 11(3), e0150355.

47

Huang YH, Hsu KH, Tseng JS, Chen KC, Su KY, Chen HY, Chang CS, Chen JJ, Yu SL, Chen HW, Yang TY, Chang GC, 2016, “Predilection of contralateral upper lung metastasis in upper lobe lung adenocarcinoma patients” J Thorac Dis., 8(1),86-92

48

Kuo TC, Li LW, Pan SH, Fang JM, Liu JH, Cheng TJ, Wang CJ, Hung PF, Chen HY, Hong TM, Hsu YL, Wong CH, Yang PC, 2016, “Purine-Type Compounds Induce Microtubule Fragmentation and Lung Cancer Cell Death through Interaction with Katanin.”, Journal of medicinal chemistry, 59(18), 8521-34.

49

Su KY, Kao JT, Ho BC, Chen HY, Chang GC, Ho CC, Yu SL, 2016, “Implementation and Quality Control of Lung Cancer EGFR Genetic Testing by MALDI-TOF Mass Spectrometry in Taiwan Clinical Practice.”, Scientific reports, 6, 30944.

50

Chih-Ken Chen, Chau-Shoun Lee, Hsuan-Yu Chen, Lawrence Shih-Hsin Wu, Jung-Chen Chang, Chia-Yih Liu, Andrew Tai-Ann Cheng, 2016, “GADL1 variant and medication adherence in predicting response to lithium maintenance treatment in bipolar I disorder”. British Journal of Psychiatry Open, 2(5), 301- 306.

51

Poyin Huang, Chiou-Ling Cheng, Ya-Hsuan Chang, Chia-Hsin Liu, Yi-Chiung Hsu, Jin-Shing Chen, Gee-Chen Chang, Bing-Ching Ho, Kang-Yi Su, Hsuan-Yu Chen*, Sung-Liang Yu*, 2016, “Molecular gene signature and prognosis of non-small cell lung cancer” Oncotarget, 7, 51898-51907.

52

Hsuan-Yu Chen*, Chia-Hsin Liu, Ya-Hsuan Chang, Sung-Liang Yu, Bing- Ching Ho, Chung-Ping Hsu, Tsung-Ying Yang, Kun-Chieh Chen, Kuo-Hsuan Hsu, Jeng-Sen Tseng, Jiun-Yi Hsia, Cheng-Yen Chuang, Chi-Sheng Chang, Yu-Cheng Li, Ker-Chau Li, Gee-Chen Chang*, Pan-Chyr Yang, 2016, “EGFR-activating mutations, DNA copy number abundance of ErbB family, and prognosis in lung adenocarcinoma”, Oncotarget, 7, 9017-9025.

53

Yang YL, Yen CT, Pai CH, Chen HY, Yu SL, Lin CY, Hu CY, Jou ST, Lin DT, Lin SR, Lin SW., 2015, “A Double Negative Loop Comprising ETV6/RUNX1 and MIR181A1 Contributes to Differentiation Block in t(12;21)-Positive Acute Lymphoblastic Leukemia.”, PLoS One, 10(11):e0142863.

54

Yuan A, Hsiao YJ, Chen HY, Chen HW, Ho CC, Chen YY, Liu YC, Hong TH, Yu SL, Chen JJ, Yang PC., 2015, “Opposite Effects of M1 and M2 Macrophage Subtypes on Lung Cancer Progression.”, Sci Rep., 5:14273.

55

Liu YN, Chang TH, Tsai MF, Wu SG, Tsai TH, Chen HY, Yu SL, Yang JC, Shih JY, 2015, “IL-8 confers resistance to EGFR inhibitors by inducing stem cell properties in lung cancer.”, Oncotarget, 6(12), 10415-31.

56

Wang CC, Su KY, Chen HY, Chang SY, Shen CF, Hsieh CH, Hong QS, Chiang CC, Chang GC, Yu SL, Chen JJ, 2015, “HOXA5 inhibits metastasis via regulating cytoskeletal remodelling and associates with prolonged survival in non-small-cell lung carcinoma.”, PloS one, 10(4), e0124191.

57

Tsai CF, Wang YT, Yen HY, Tsou CC, Ku WC, Lin PY, Chen HY, Nesvizhskii AI, Ishihama Y, Chen YJ, 2015, “Large-scale determination of absolute phosphorylation stoichiometries in human cells by motif-targeting quantitative proteomics.”, Nature communications, 6, 6622.

58

Hsu KH, Ho CC, Hsia TC, Tseng JS, Su KY, Wu MF, Chiu KL, Yang TY, Chen KC, Ooi H, Wu TC, Chen HJ, Chen HY, Chang CS, Hsu CP, Hsia JY, Chuang CY, Lin CH, Chen JJ, Chen KY, Liao WY, Shih JY, Yu SL, Yu CJ, Yang PC, Chang GC, 2015, “Identification of five driver gene mutations in patients with treatment-naive lung adenocarcinoma in Taiwan.”, PloS one, 10(3), e0120852.

59

Liao WY, Ho CC, Hou HH, Hsu TH, Tsai MF, Chen KY, Chen HY, Lee YC, Yu CJ, Lee CH, Yang PC, 2015, “Heparin co-factor II enhances cell motility and promotes metastasis in non-small cell lung cancer.”, Journal of pathology, 235(1), 50-64.

60

Ho BC, Yu IS, Lu LF, Rudensky A, Chen HY, Tsai CW, Chang YL, Wu CT, Chang LY, Shih SR, Lin SW, Lee CN, Yang PC, Yu SL, 2014, “Inhibition of miR-146a prevents enterovirus-induced death by restoring the production of type I interferon.”, Nature communications, 5, 3344.

61

Chen WJ, Ho CC, Chang YL, Chen HY, Lin CA, Ling TY, Yu SL, Yuan SS, Chen YJ, Lin CY, Pan SH, Chou HY, Chen YJ, Chang GC, Chu WC, Lee YM, Lee JY, Lee PJ, Li KC, Chen HW, Yang PC, 2014, “Cancer-associated fibroblasts regulate the plasticity of lung cancer stemness via paracrine signalling.”, Nature communic ations, 5, 3472.

62

Tseng JS, Yang TY, Chen KC, Hsu KH, Yu CJ, Liao WY, Tsai CR, Tsai MH, Yu SL, Su KY, Chen JJ, Chen HY, Chang GC, 2014, “Prior EGFR tyrosine-kinase inhibitor therapy did not influence the efficacy of subsequent pemetrexed plus platinum in advanced chemonaive patients with EGFR-mutant lung adenocarcinoma.”, OncoTargets and therapy, 7, 799-805.

63

Lee JH, Lin YL, Hsu WH, Chen HY, Chang YC, Yu CJ, Shih JY, Lin CC, Chen KY, Ho CC, Laio WY, Yang PC, Yang JC, 2014, “Bcl-2-like protein 11 deletion polymorphism predicts survival in advanced non-small-cell lung cancer.”, Journal of thoracic oncology, 9(9), 1385-92.

64

Wang LK, Hsiao TH, Hong TM, Chen HY, Kao SH, Wang WL, Yu SL, Lin CW, Yang PC, 2014, “MicroRNA-133a suppresses multiple oncogenic membrane receptors and cell invasion in non-small cell lung carcinoma.”, PloS one, 9(5), e96765.

65

Chen KC, Chen HY, Lin JW, Tseng YT, Kuo SW, Huang PM, Hsu HH, Lee JM, Chen JS, Lai HS, 2014, “Acute thoracic empyema: clinical characteristics and outcome analysis of video-assisted thoracoscopic surgery.”, JOURNAL OF THE FORMOSAN MEDICAL ASSOCIATION, 113(4), 210-8.

66

Chen CC, Chen HY, Su KY, Hong QS, Yan BS, Chen CH, Pan SH, Chang YL, Wang CJ, Hung PF, Yuan S, Chang GC, Chen JJ, Yang PC, Yang YC, Yu SL, 2014, “Shisa3 is associated with prolonged survival through promoting beta-catenin degradation in lung cancer.”, American journal of respiratory and critical care medicine, 190(4), 433-44.

67

Hsu PK, Chen HY, Yeh YC, Yen CC, Wu YC, Hsu CP, Hsu WH, Chou TY, 2014, “TPX2 expression is associated with cell proliferation and patient outcome in esophageal squamous cell carcinoma.”, Journal of gastroenterology, 49(8), 1231-40.

68

Hsu PK, Kao HL, Chen HY, Yen CC, Wu YC, Hsu WH, Chou TY, 2014, “Loss of CRNN expression is associated with advanced tumor stage and poor survival in patients with esophageal squamous cell carcinoma.”, Journal of thoracic and cardiovascular surgery, 147(5), 1612-1618.e4.

69

Hsu YC, Chen HY, Yuan S, Yu SL, Lin CH, Wu G, Yang PC, Li KC, 2013, “Genome-wide analysis of three-way interplay among gene expression, cancer cell invasion and anti-cancer compound sensitivity.”, BMC medicine, 11, 106.

70

Wu P, Yuan SS, Ho CC, Hsieh WY, Hong QS, Yu SL, Chen W, Chen HY, Wang CD, Li KC, Yang PC, Chen HW, 2013, “Focal amplification of HOXD-harboring chromosome region is implicated in multiple-walled carbon nanotubes-induced carcinogenicity.”, Nano letters, 13(10), 4632-41.

71

Lai YH, Yu SL, Chen HY, Wang CC, Chen HW, Chen JJ, 2013, “The HLJ1-targeting drug screening identified Chinese herb andrographolide that can suppress tumour growth and invasion in non-small-cell lung cancer.”, Carcinogenesis, 34(5), 1069-80.

72

Hung PF, Hong TM, Hsu YC, Chen HY, Chang YL, Wu CT, Chang GC, Jou YS, Pan SH, Yang PC, 2013, “The motor protein KIF14 inhibits tumor growth and cancer metastasis in lung adenocarcinoma.”, PloS one, 8(4), e61664.

73

Lin CW, Chang YL, Chang YC, Lin JC, Chen CC, Pan SH, Wu CT, Chen HY, Yang SC, Hong TM, Yang PC, 2013, “MicroRNA-135b promotes lung cancer metastasis by regulating multiple targets in the Hippo pathway and LZTS1.”, Nature communications, 4, 1877.

74

Chen HY, Yu SL, Li KC, and Yang PC, 2012, “Biomarkers and transcriptome profiling of lung cancer”, RESPIROLOGY, 17, 620-6.

75

Kang-Yi Su, Hsuan-Yu Chen, Ker-Chau Li, Ming-Liang Kuo, James Chih-Hsin Yang, Wing-Kai Chan, Bing-Ching Ho, Gee-Chen Chang, Jin-Yuan Shih, Sung-Liang Yu, Pan-Chyr Yang, 2012, “Pretreatment Epidermal Growth Factor Receptor (EGFR) T790M Mutation Predicts Shorter EGFR Tyrosine Kinase Inhibitor Response Duration in Patients With Non–Small-Cell Lung Cancer”, JOURNAL OF CLINICAL ONCOLOGY, 30(4), 433-440.

76

Tseng JS, Yang TY, Chen KC, Hsu KH, Chen HY, Chang GC, 2012, “Retrospective study of erlotinib in patients with advanced squamous lung cancer.”, LUNG CANCER, 77(1), 128-33.

77

Yang YL, Hsiao CC, Chen HY, Lin KH, Jou ST, Chen JS, Chang TK, Sheen JM, Yu SL, Lu MY, Cheng CN, Wu KH, Wang SC, Wang JD, Chang HH, Lin SR, Lin SW, Lin DT, 2012, “Absence of biallelic TCRgamma deletion predicts induction failure and poorer outcomes in childhood T-cell acute lymphoblastic leukemia.”, Pediatric blood & cancer, 58(6), 846-51.

78

Wan-Yu Hsieh, Cheng-Chung Chou, Chao-Chi Ho, Sung-Liang Yu, Hsuan-Yu Chen, Han-Yi E. Chou, Jeremy J. W. Chen, Huei-Wen Chen*, and Pan-Chyr Yang*, 2012, “Single-Walled Carbon Nanotubes Induce Arirway Hyperreactivity and Parenchymal Injury in Mice”, AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 46, 257-267.

79

Emura T, Chen YH, Chen HY, 2012, “Survival prediction based on compound covariate under Cox proportional hazard models.”, PloS one, 7(10), e47627.

80

Lin IH, Ho ML, Chen HY, Lee HS, Huang CC, Chu YH, Lin SY, Deng YR, He YH, Lien YH, Hsu CW, Wong RH, 2012, “Smoking, green tea consumption, genetic polymorphisms in the insulin-like growth factors and lung cancer risk.”, PloS one, 7(2), e30951.

81

Yang YL, Hung CC, Chen JS, Lin KH, Jou ST, Hsiao CC, Sheen JM, Cheng CN, Wu KH, Lin SR, Yu SL, Chen HY, Lu MY, Wang SC, Chang HH, Lin SW, Su YN, Lin DT., 2011, “IKZF1 deletions predict a poor prognosis in children with B-cell progenitor acute lymphoblastic leukemia: a multicenter analysis in Taiwan”, CANCER SCIENCE, 102 (10 ), 1874-1881.

82

Chiang HH, Hung CC, Lee CM, Chen HY, Chen MY, Sheng WH, Hsieh SM, Sun HY, Ho CC, Yu CJ., 2011, “Admissions to intensive care unit of HIV-infected patients in the era of highly active antiretroviral therapy: etiology and prognostic factors”, CRITICAL CARE, 15(4), R202.

83

Kuo-Hsuan Hsu, Kun-Chieh Chen, Tsung-Ying Yang, Yi-Chen Yeh, Teh-Ying Chou, Hsuan-Yu Chen, Chi-Rne Tsai, Chih-Yi Chen, Chung-Ping Hsu, Jiun-Yi Hsia, Cheng-Yen Chuang, Ying-Huang Tsai, Kuan-Yu Chen, Ming-Shyan Huang, Wu-Chou Su, Yuh-Min Chen, Chao A. Hsiung, Gee-Chen Chang, Chien-Jen Chen, Pan-Chyr Yang, 2011, “Epidermal Growth Factor Receptor Mutation Status in Stage I Lung Adenocarcinoma with Different Image Patterns”, Journal of Thoracic Oncology, 6(6), 1066-1072.

84

Nakagawa-Goto K, Wu PC, Bastow KF, Yang SC, Yu SL, Chen HY, Lin JC, Goto M, Morris-Natschke SL, Yang PC, Lee KH, 2011, “Antitumor agents 283. Further elaboration of desmosdumotin C analogs as potent antitumor agents: activation of spindle assembly checkpoint as possible mode of action”, Bioorg Med Chem, 19(5),1816-22.

85

Pan SH, Chao YC, Hung PF, Chen HY, Yang SC, Chang YL, Wu CT, Chang CC, Wang WL, Chan WK, Wu YY, Che TF, Wang LK, Lin CY, Lee YC, Kuo ML, Lee CH, Chen JJ, Hong TM, Yang PC, 2011, “The ability of LCRMP-1 to promote cancer invasion by enhancing filopodia formation is antagonized by CRMP-1.”, JOURNAL OF CLINICAL INVESTIGATION, 121(8), 3189-205.

86

Wu SG, Chang YL, Lin JW, Wu CT, Chen HY, Tsai MF, Lee YC, Yu CJ, Shih JY, 2011, “Including Total EGFR Staining in Scoring Improves EGFR Mutations Detection by Mutation-Specific Antibodies and EGFR TKIs Response Prediction.”, PloS one, 6(8), e23303.

87

Yuan S, Yu SL, Chen HY, Hsu YC, Su KY, Chen HW, Chen CY, Yu CJ, Shih JY, Chang YL, Cheng CL, Hsu CP, Hsia JY, Lin CY, Wu G, Liu CH, Wang CD, Yang KC, Chen YW, Lai YL, Hsu CC, Lin TC, Yang TY, Chen KC, Hsu KH, Chen JJ, Chang GC, Li KC, Yang PC, 2011, “Clustered Genomic Alterations in Chromosome 7p Dictate Outcomes and Targeted Treatment Responses of Lung Adenocarcinoma With EGFR-Activating Mutations.”, JOURNAL OF CLINICAL ONCOLOGY, 29(25), 3435-42.

88

Bing-Ching Ho, Sung-Liang Yu, Jeremy J.W. Chen, Sui-Yuan Chang, Bo-Shiun Yan, Qi-Sheng Hong, Sher Singh, Chuan-Liang Kao, Hsuan-Yu Chen, Kang-Yi Su, Ker-Chau Li, Chiou-Ling Cheng, Hao-Wei Cheng, Jen-Yi Lee, Chun-Nan Lee, Pan-Chyr Yang, 2011, “Enterovirus-Induced miR-141 Contributes to Shutoff of Host Protein Translation by Targeting the Translation Initiation Factor eIF4E”, Cell Host & Microbe, 9(1), 58.

89

Lai CY, Yu SL, Hsieh MH, Chen CH, Chen HY, Wen CC, Huang YH, Hsiao PC, Hsiao CK, Liu CM, Yang PC, Hwu HG, Chen WJ, 2011, “MicroRNA expression aberration as potential peripheral blood biomarkers for schizophrenia.”, PloS one, 6(6), e21635.

90

Pan SH, Chao YC, Chen HY, Hung PF, Lin PY, Lin CW, Chang YL, Wu CT, Lee YC, Yang SC, Hong TM, Yang PC., 2010, “Long form collapsin response mediator protein-1 (LCRMP-1) expression is associated with clinical outcome and lymph node metastasis in non-small cell lung cancer patients.”, Lung Cancer, 67(1):93-100.

91

PY Lin, YC Chang, HY Chen, HC Tsui, PC Yang, 2010, “Tumor size matters differently in pulmonary adenocarcinoma and squamous cell carcinoma”, LUNG CANCER, 67, 296-300.

92

Yang YL, Lin SR, Chen JS, Hsiao CC, Lin KH, Sheen JM, Cheng CN, Wu KH, Lin SW, Yu SL, Chen HY, Lu MY, Chang HH, Yen CT, Lin JF, Su YH, Li YP, Lin CY, Jou ST, Lin DT, 2010, “Multiplex reverse transcription-polymerase chain reaction as diagnostic molecular screening of 4 common fusion chimeric genes in Taiwanese children with acute lymphoblastic leukemia.”, Journal of pediatric hematology oncology, 32(8), e323-30.

93

Yang YL, Lin SR, Chen JS, Lin SW, Yu SL, Chen HY, Yen CT, Lin CY, Lin JF, Lin KH, Jou ST, Hu CY, Chang SK, Lu MY, Chang HH, Chang WH, Lin KS, Lin DT, 2010, “Expression and prognostic significance of the apoptotic genes BCL2L13, Livin, and CASP8AP2 in childhood acute lymphoblastic leukemia.”, Leukemia research, 34(1), 18-23.

94

Chen, Hsuan-Yu; Yang, Pan-Chyr, 2009, “Molecular Biomarker for Lung Cancer.”, NEW TRENDS IN THE MOLECULAR AND BIOLOGICAL BASIS FOR CLINICAL ONCOLOGY, DOI: 10.1007/978-4-431-88663-1_9.

95

Lin JC, Yang SC, Hong TM, Yu SL, Shi Q, Wei L, Chen HY, Yang PC, Lee KH., 2009, “Phenanthrene-based tylophorine-1 (PBT-1) inhibits lung cancer cell growth through the Akt and NF-kappaB pathways.”, J Med Chem, 52(7):1903-11.

96

Hsu, Yi-Chiung, Yuan, Shinsheng, Chen, Hsuan-Yu*, Yu, Sung-Liang, Liu, Chia-Hsin, Hsu, Pin-Yen, Wu, Guani, Lin, Chia-Hung, Chang, Gee-Chen, Li, Ker-Chau, Yang, Pan-Chyr , 2009, “A Four-Gene Signature from NCI-60 Cell Line for Survival Prediction in Non-Small Cell Lung Cancer ”, Clinical Cancer Research, 15(23), 7309-7315

97

Chen, Cheng-Yu, Yang, Kuang-Yao, Chen, Mei-Yu, Chen, Hsuan-Yu, Lin, Ming-Tzer, Lee, Yu-Chin, Perng, Reury-Perng, Hsieh, , 2009, “Decoy Receptor 3 Levels in Peripheral Blood Predict Outcomes of Acute Respiratory Distress Syndrome ”, American Journal of Respiratory and Critical Care Medicine, 180(8), 751-760.

98

Lin, Jau-Chen, Yang, Shuenn-Chen, Hong, Tse-Ming, Yu, Sung-Liang, Shi, Qian, Wei, Linyi, Chen, Hsuan-Yu, Yang, Pan-Chyr, Leo, Kuo-Hsiung, 2009, “Phenanthrene-Based Tylophorine-1 (PBT-1) Inhibits Lung Cancer Cell Growth through the Akt and NF-kappa B Pathways”, Journal of Medicinal Chemistry, 52(7), 1903-1911.

99

Shih TT, Hou HA, Liu CY, Chen BB, Tang JL, Chen HY, Wei SY, Yao M, Huang SY, Chou WC, Hsu SC, Tsay W, Yu CW, Hsu CY, Tien HF, Yang PC, 2009, “Bone marrow angiogenesis magnetic resonance imaging in patients with acute myeloid leukemia: peak enhancement ratio is an independent predictor for overall survival.”, Blood, 113(14), 3161-3167.

100

Liu WH, Yeh SH, Lu CC, Yu SL, Chen HY, Lin CY, Chen DS, Chen PJ, 2009, “MicroRNA-18a prevents estrogen receptor-alpha expression, promoting proliferation of hepatocellular carcinoma cells.”, Gastroenterology, 136(2), 683-693.

101

Yu SL, Chen HY, Chang GC, Chen CY, Chen HW, Singh S, Cheng CL, Yu CJ, Lee YC, Chen HS, Su TJ, Chiang CC, Li HN, Hong QS, Su HY, Chen CC, Chen WJ, Liu CC, Chan WK, Chen WJ, Li KC, Chen JJ, Yang PC, 2008, “MicroRNA signature predicts survival and relapse in lung cancer.”, Cancer cell, 13, 48-57.

102

Ho CC, Liao WY, Wang CY, Lu YH, Huang HY, Chen HY, Chan WK, Chen HW, Yang PC, 2008, “TREM-1 expression in tumor-associated macrophages and clinical outcome in lung cancer.”, American journal of respiratory and critical care medicine, 177(7), 763-770.

103

Yu SL, Singh S, Chen HW, Chen HY, Chen JJ, Chen WJ, Chen HS, Chen SC, 2008, “Intra-abdominal adhesion formation induces anti-oxidative injury, enhances cell proliferation, and prevents complement-mediated lysis.”, WOUND REPAIR AND REGENERATION, 16(3), 388-398.

104

Chen, Hsuan-Yu; Chen, Wei J.; Yang, Pan-Chyr, 2007, “Five-gene signature in non-small-cell lung cancer - Reply”, New England Journal of Medicine, 356(15):1583-1583.

105

Yu SL, Chen HY, Yang PC, Chen JJ, 2007, “Unique MicroRNA signature and clinical outcome of cancers.”, DNA and cell biology, 26(5), 283-292.

106

Liu CC, Lin CC, Chen WS, Chen HY, Chang PC, Chen JJ, Yang PC, 2006, “CRSD: a comprehensive web server for composite regulatory signature discovery.”, Nucleic acids research, 34(Web Server issue), W571-W577.

107

Liu CC, Chen WS, Lin CC, Liu HC, Chen HY, Yang PC, Chang PC, Chen JJ, 2006, “Topology-based cancer classification and related pathway mining using microarray data.”, Nucleic acids research, 34(14), 4069-4080.

108

Tsai MF, Wang CC, Chang GC, Chen CY, Chen HY, Cheng CL, Yang YP, Wu CY, Shih FY, Liu CC, Lin HP, Jou YS, Lin SC, Lin CW, Chen WJ, Chan WK, Chen JJ, Yang PC, 2006, “A new tumor suppressor DnaJ-like heat shock protein, HLJ1, and survival of patients with non-small-cell lung carcinoma.”, Journal of the National Cancer Institute, 98(12), 825-838.

109

Chen JJ, Lin YC, Yao PL, Yuan A, Chen HY, Shun CT, Tsai MF, Chen CH, Yang PC, 2005, “Tumor-associated macrophages: the double-edged sword in cancer progression.”, JOURNAL OF CLINICAL ONCOLOGY, 23(5), 953-964.

110

Chen WJ, Chen HW, Yu SL, Huang CH, Wang TD, Chen JJ, Chien CT, Chen HY, Yang PC, Lee YT, 2005, “Gene expression profiles in hypoxic preconditioning using cDNA microarray analysis: altered expression of an angiogenic factor, carcinoembryonic antigen-related cell adhesion molecule 1.”, SHOCK, 24(2), 124-131.

111

Chou WC, Chen HY, Yu SL, Cheng L, Yang PC, Dang CV, 2005, “Arsenic suppresses gene expression in promyelocytic leukemia cells partly through Sp1 oxidation.”, Blood, 106(1), 304-310.